Last 7 days
Bookmark and Share    
Full Text
Peer Reviewed
See detailDynamic force spectroscopy of synthetic oligorotaxane foldamers
Sluysmans, Damien ULiege; Devaux, Floriane ULiege; Bruns, Carson J. et al

in Proceedings of the National Academy of Sciences of the United States of America (in press)

Wholly synthetic molecules involving both mechanical bonds and a folded secondary structure are one of the most promising architec- tures for the design of functional molecular machines with un ... [more ▼]

Wholly synthetic molecules involving both mechanical bonds and a folded secondary structure are one of the most promising architec- tures for the design of functional molecular machines with un- precedented properties. Here, we report dynamic single-molecule force spectroscopy experiments that explore the energetic details of donor–acceptor oligorotaxane foldamers, a class of molecular switches. The mechanical breaking of the donor–acceptor interactions responsible for the folded structure shows a high constant rupture force over a broad range of loading rates, covering three orders of magnitude. In comparison with dynamic force spectroscopy performed during the past 20 y on various (bio)molecules, the near-equilibrium regime of oligorotaxanes persists at much higher loading rates, at which bio- molecules have reached their kinetic regime, illustrating the very fast dynamics and remarkable rebinding capabilities of the intramolecular donor–acceptor interactions. We focused on one single interaction at a time and probed the stochastic rupture and rebinding paths. Using the Crooks fluctuation theorem, we measured the mechanical work produced during the breaking and rebinding to determine a free- energy difference, ΔG, of 6 kcal·mol−1 between the two local confor- mations around a single bond. [less ▲]

Detailed reference viewed: 28 (5 ULiège)
Full Text
Peer Reviewed
See detailNouns and pronouns
Maillart, Christelle ULiege; Parisse, Christophe

in Damico, Jack, S.; Ball, Martin, J. (Eds.) The SAGE Encyclopedia of Communication Sciences and Disorders (in press)

Detailed reference viewed: 7 (0 ULiège)
Full Text
Peer Reviewed
See detailDeterminers
Parisse, Christophe; Maillart, Christelle ULiege

in Damico, Jack; Ball, Martin, S. (Eds.) The SAGE Encyclopedia of Communication Sciences and Disorders (in press)

Detailed reference viewed: 17 (0 ULiège)
Full Text
See detailRegimes of Responsibility in Africa: Genealogies, Rationalities and Conflicts
Jedlowski, Alessandro ULiege

Book published by Berghahn (in press)

This edited collection of essays analyses the transformations that discourses and practices of responsibility have undergone in Africa since the early 1990s. In most of the continent’s countries, this ... [more ▼]

This edited collection of essays analyses the transformations that discourses and practices of responsibility have undergone in Africa since the early 1990s. In most of the continent’s countries, this period has been marked by the introduction of neoliberal reforms, partial liberalization of the political landscape, increased foreign investment, the multiplication of religious movements, the exponential growth of migration fluxes, the emergence of new media, and the explosion of the AIDS pandemic. The core assumption of the book is that these phenomena have significantly modified the way responsibility is imagined, discussed and organized in African societies, and have contributed to transforming this concept into one of the key moral ideas by which these societies think about, and act upon their present and future power configurations. To discuss this central hypothesis, the book’s contributions examine discourses and practices of responsibility in nine different settings, and reflect on the broader changes in regimes of responsibility to which they take part. By doing so, this collection of essays will offer insight that develop a stronger grasp on the interaction between moral practices and discourses, and specific political, economic and social transformations taking place today in Africa. At the same time, while focusing on case studies from the African continent, this collection enters into a dialogue with the emerging corpus of studies in the field of ethics, providing to it a set of analytical perspectives that can help further enlarge its theoretical and geographical scope. [less ▲]

Detailed reference viewed: 16 (0 ULiège)
Full Text
See detailCine-Ethiopia: The History and Politics of Film in the Horn of Africa
Jedlowski, Alessandro ULiege

Book published by Michigan State University Press (in press)

Over the past decade, Ethiopian films have come to dominate the screening schedules of the many cinemas in Ethiopia’s capital city Addis Ababa and other urban centers. Despite undergoing an unprecedented ... [more ▼]

Over the past decade, Ethiopian films have come to dominate the screening schedules of the many cinemas in Ethiopia’s capital city Addis Ababa and other urban centers. Despite undergoing an unprecedented surge in production and popularity in Ethiopia and in the diaspora, this phenomenon has been broadly overlooked by African film and media scholars and Ethiopianists alike. This collection of essays and interviews on cinema in Ethiopia represents the first work of its kind and establishes a broad foundation for the furthering of the scholarship. Taking an interdisciplinary approach to the topic and bringing together contributions from both Ethiopian and international scholars, the collection offers new and alternative narratives for the development of screen media in Africa. The book’s relevance reaches far beyond its specific locale of Ethiopia as contributions focus on a broad range of topics such as commercial and genre films, diaspora filmmaking and the role of women in the film industry while discussing multiple forms of screen media, from satellite TV to “video films”. Bringing both the historical and contemporary moments of cinema in Ethiopia into the critical frame offers alternative considerations for the already radically changing critical paradigm surrounding the understandings of “African Cinema.” [less ▲]

Detailed reference viewed: 18 (0 ULiège)
Full Text
Peer Reviewed
See detailAfrican videoscapes: Southern Nigeria, Ethiopia and Côte d’Ivoire in comparative perspective
Jedlowski, Alessandro ULiege

in Harrow, Kenneth (Ed.) Companion to African Cinema (in press)

With the introduction of analogue and (later) digital technologies, many sub-Saharan African countries have witnessed the emergence and rapid growth of commercial video film industries. The Nigerian ... [more ▼]

With the introduction of analogue and (later) digital technologies, many sub-Saharan African countries have witnessed the emergence and rapid growth of commercial video film industries. The Nigerian industry, Nollywood, is the case studies that raised most scholarly interest, generating the formulation of an analytical model which has often influenced our understanding of other instances of video film production around the continent. This chapter proposes a comparative analysis of the history of video filmmaking in three sub-Saharan African countries (Nigeria, Ethiopia and Côte d’Ivoire) in order to complicate our understanding of African video film beyond the Nollywood model. Drawing from ethnographic materials collected during fieldwork conducted in each of these countries, this chapter offers an original contribution to the existing debate on the impact of analogue and digital technologies on the transformation of African cinema which highlight the impact of specific local political, economic, and infrastructural contexts on the development of video film industries around the continent. [less ▲]

Detailed reference viewed: 25 (0 ULiège)
Full Text
Peer Reviewed
See detailToward new African languages of protest: African documentary films and human rights
Jedlowski, Alessandro ULiege

in Hjort, Mette (Ed.) African Cinema and Human Rights (in press)

With the introduction of new recording and editing technologies, documentary film production has witnessed important growth and diversification, but the process of creating and consolidating a viable and ... [more ▼]

With the introduction of new recording and editing technologies, documentary film production has witnessed important growth and diversification, but the process of creating and consolidating a viable and solid documentary film production environment still faces numerous challenges which must be the necessary starting point for any thorough discussion of the relationship between documentary films and human rights in Africa today. In order to tackle these issues, this chapter begins with a section that, through the discussion of a wide range of materials collected between 2012 and 2013 for a continent-wide, team-based research project on the state of the documentary film industry across Africa, provides a comprehensive (although inevitably general) analysis of the main challenges that African documentary filmmakers face today. This analysis opens up the space for a critical discussion of the interaction between human rights discourses and documentary film production in the continent. Human rights discourses have been the object of much scholarly debate in Africa, and a discussion of these debates in relation to the challenges highlighted in the first section helps better understanding the field of tensions within which African documentary filmmakers are operating and the original aesthetic and narrative solutions that are emerging from it. [less ▲]

Detailed reference viewed: 23 (0 ULiège)
Full Text
Peer Reviewed
See detailRecursion
Parisse, Christophe; Maillart, Christelle ULiege

in Damico, Jack; Ball, Martin (Eds.) The SAGE Encyclopedia of Communication Sciences and Disorders (in press)

Detailed reference viewed: 14 (1 ULiège)
See detailLa rencontre de juillet-août 1529
Fagnart, Laure ULiege; Le Roux, Nicolas

in La 'paix des Dames', entre politique, mises en scène du pouvoir et célébrations (in press)

Detailed reference viewed: 17 (0 ULiège)
See detailIntroduction
Fagnart, Laure ULiege

in La 'paix des Dames', entre politique, mises en scène du pouvoir et célébrations (in press)

Detailed reference viewed: 9 (0 ULiège)
Full Text
Peer Reviewed
See detailSynthetic oligorotaxanes exert high forces when folding under mechanical load
Sluysmans, Damien ULiege; Hubert, Sandrine ULiege; Bruns, Carson et al

in Nature Nanotechnology (in press)

Folding is a ubiquitous process that nature uses to control the conformations of its molecular machines, allowing them to perform chemical and mechanical tasks. Over the years, chemists have synthesized ... [more ▼]

Folding is a ubiquitous process that nature uses to control the conformations of its molecular machines, allowing them to perform chemical and mechanical tasks. Over the years, chemists have synthesized foldamers that adopt well-defined and stable folded architectures, mimicking the control expressed by natural systems. Mechanically interlocked molecules, such as rotaxanes and catenanes, are prototypical molecular machines that enable the controlled movement and positioning of their component parts. Recently, combining the exquisite complexity of these two classes of molecules, donor–acceptor oligorotaxane foldamers have been synthesized, in which interactions between the mechanically interlocked component parts dictate the single-molecule assembly into a folded secondary structure. Here we report on the mechanochemical properties of these molecules. We use atomic force microscopy-based single-molecule force spectroscopy to mechanically unfold oligorotaxanes, made of oligomeric dumbbells incorporating 1,5-dioxynaphthalene units encircled by cyclobis(paraquat-p-phenylene) rings. Real-time capture of fluctuations between unfolded and folded states reveals that the molecules exert forces of up to 50 pN against a mechanical load of up to 150 pN, and displays transition times of less than 10 μs. While the folding is at least as fast as that observed in proteins, it is remarkably more robust, thanks to the mechanically interlocked structure. Our results show that synthetic oligorotaxanes have the potential to exceed the performance of natural folding proteins. [less ▲]

Detailed reference viewed: 20 (3 ULiège)
Peer Reviewed
See detailXénophane de Colophon et l’approche critique du religieux
Fortier, Simon ULiege

in Collette, Bernard; Gavray, Marc-Antoine; Narbonne, Jean-Marc (Eds.) Raison et Révélation : l’Héritage Critique de l’Antiquité, Volume I : Le développement de l’esprit critique dans l’Antiquité (in press)

Detailed reference viewed: 17 (0 ULiège)
Peer Reviewed
See detailTraité 31 [V, 8]
Fortier, Simon ULiege

in Narbonne, Jean-Marc (Ed.) Plotin, Œuvres complètes, tome II, vol. II (in press)

Detailed reference viewed: 14 (0 ULiège)
Full Text
Peer Reviewed
See detailThe X-ray footprint of the CircumNuclear Disk
Mossoux, Enmanuelle ULiege; Eckart, Andreas

in Monthly Notices of the Royal Astronomical Society (in press)

We studied the central regions of the Galactic Centre to determine if the CircumNuclear Disk (CND) acts as an absorber or a barrier for the central X-rays diffuse emission. After reprocessing 4.6Ms of ... [more ▼]

We studied the central regions of the Galactic Centre to determine if the CircumNuclear Disk (CND) acts as an absorber or a barrier for the central X-rays diffuse emission. After reprocessing 4.6Ms of Chandra observations, we were able to detect, for the first time, a depression in the X-ray luminosity of the diffuse emission whose size and location correspond to those of the CND. We extracted the X-ray spectra for various regions inside the CND footprint as well as for the region where the footprint is observed and for a region located outside the footprint. We simultaneously fitted these spectra as an optically thin plasma whose absorption by the interstellar medium and by the local plasma were fitted independently using the MCMC method. The hydrogen column density of the ISM is 7.5x10^22 cm^-2. The X-ray diffuse emission inside the CND footprint is formed by a 2T plasma of 1 and 4keV with slightly super-solar abundances except for the iron and carbon which are sub-solar. The plasma from the CND, in turn, is better described by a 1T model with abundances and local hydrogen column density which are very different to those of the innermost regions. The large iron abundance in this region confirms that the CND is dominated by the shock-heated ejecta of the Sgr A East supernova remnant. We deduced that the CND rather acts as a barrier for the Galactic Centre plasma and that the plasma located outside the CND may correspond to the collimated outflow possibly created by Sgr A* or the interaction between the wind of massive stars and the mini-spiral material. [less ▲]

Detailed reference viewed: 25 (0 ULiège)
Full Text
Peer Reviewed
See detailSolid-liquid suspension of microcarriers in stirred tank bioreactor - Experimental and numerical analysis
Delafosse, Angélique ULiege; Loubière, Céline; Calvo, Sébastien ULiege et al

in Chemical Engineering Science (in press)

Detailed reference viewed: 18 (0 ULiège)
Full Text
Peer Reviewed
See detailIntégrer le droit international au champ des relations internationales : les juristes belges à Versailles en 1919
Genin, Vincent ULiege

in Relations internationales (in press), (2),

Detailed reference viewed: 19 (0 ULiège)
Full Text
Peer Reviewed
See detailDiagnostic, pronostic et traitements des troubles de la conscience
Cassol, Helena ULiege; Aubinet, Charlène ULiege; Thibaut, Aurore ULiege et al

in NPG. Neurologie - Psychiatrie - Gériatrie (in press)

Les progrès de la médecine et des soins intensifs ont conduit à une augmentation du nombre de patients survivant à une lésion cérébrale sévère. Bien que certains patients récupèrent rapidement, d’autres ... [more ▼]

Les progrès de la médecine et des soins intensifs ont conduit à une augmentation du nombre de patients survivant à une lésion cérébrale sévère. Bien que certains patients récupèrent rapidement, d’autres demeurent dans un état de conscience altérée (ECA). Ces derniers peuvent évoluer du coma vers un état végétatif/syndrome d'éveil non répondant (EV/ENR), puis vers un état de conscience minimale (ECM). Dans cette revue, nous proposons tout d’abord de décrire les différentes méthodes, comportementales et de neuro-imagerie, utilisées dans le diagnostic des patients en ECA. Nous décrirons ensuite les facteurs susceptibles d’influencer le pronostic et la récupération de ces patients, ainsi que les traitements et la prise en charge qui peuvent être proposés dans le but d’améliorer leur état de conscience. Enfin, nous clôturerons cette revue avec une réflexion sur les considérations éthiques et les questions de fin de vie. [less ▲]

Detailed reference viewed: 49 (0 ULiège)
Full Text
Peer Reviewed
See detailPotential for the use of lactoperoxidase against post-harvest diseases on fruit
Bafort, Françoise ULiege; Perraudin, Jean-Paul; Jijakli, Haissam ULiege

in IV International Symposium on Postharvest Pathology (in press)

Detailed reference viewed: 13 (0 ULiège)
See detailItinéraires du livre italien à la Renaissance : regards sur la Suisse romande, les anciens Pays-Bas et la Principauté de Liège
Adam, Renaud ULiege; Lastraioli, Chiara

Book published by Classiques Garnier (in press)

Detailed reference viewed: 15 (0 ULiège)