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See detailLa place de l’éthique dans la clinique du lien social
Englebert, Jérôme ULg; Gesché, Michèle; Kalonji, Johan

Conference (2017, June 09)

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See detailFire resistance of concrete slabs acting in compressive membrane action
Molkens, Tom; Gernay, Thomas ULg; Caspeele, Robby

in Proceedings of the 2nd International Fire Safety Symposium - IFireSS 2017 (2017, June 08)

In building renovation, the real behaviour of reinforced concrete slabs cannot always be explained by the bending theory according to classical structural mechanics. Indeed, the bearing capacity, as ... [more ▼]

In building renovation, the real behaviour of reinforced concrete slabs cannot always be explained by the bending theory according to classical structural mechanics. Indeed, the bearing capacity, as assessed for instance by a loading test, sometimes appears to be much higher than what would be expected. This phenomenon may be caused by the activation of an arch-effect or so-called compressive membrane action (CMA) which can develop even with small vertical deformations. For a slab which is completely restrained, the presence of reinforcement becomes of lesser importance when this phenomenon is activated (except for end fields). Hence, for fire resistance purposes, it can be discussed whether reinforcement and concrete cover has a smaller influence on the bearing capacity for slabs subjected to fire which exhibit a significant concrete compressive membrane behaviour. This paper presents a loading test performed on a real concrete building which highlighted the development of CMA as the load bearing mode. It then proposes a strategy to evaluate the behaviour resulting from the development of CMA in reinforced concrete slabs at ambient and at elevated temperature based on numerical modelling. The numerical analyses are performed with the finite element software SAFIR® using a strip of layered shell elements. A plastic-damage constitutive model with an explicit transient creep formulation is used to capture the concrete behaviour at elevated temperature. [less ▲]

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See detailPRP & arthrose
Kaux, Jean-François ULg

Conference (2017, June 02)

Les injections de Plasma Riche en Plaquettes (PRP) dans le traitement de diverses pathologies arthrosiques semblent se développer comme un nouveau traitement de pointe. Sur base de ce constat, nous avons ... [more ▼]

Les injections de Plasma Riche en Plaquettes (PRP) dans le traitement de diverses pathologies arthrosiques semblent se développer comme un nouveau traitement de pointe. Sur base de ce constat, nous avons relevé dans la littérature, les conditions de protocoles d’optimisation du traitement du PRP dans les lésions cartilagineuses. [less ▲]

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See detailIntérêt de la cryothérapie chez le sportif
Kaux, Jean-François ULg

Conference (2017, June 02)

La thérapie par le froid est couramment utilisée comme une procédure pour soulager les symptômes douloureux, particulièrement dans les maladies inflammatoires. La cryothérapie corps entier consiste en une ... [more ▼]

La thérapie par le froid est couramment utilisée comme une procédure pour soulager les symptômes douloureux, particulièrement dans les maladies inflammatoires. La cryothérapie corps entier consiste en une exposition à l’air très froid (maintenue entre -110 °C et -140 °C) en cryochambre spéciale, généralement pendant 2 minutes. En médecine sportive, la cryothérapie corps entier a gagné en popularité comme méthode améliorant la récupération ou accélérant la guérison des blessures. Malheureusement, il n’y a peu de documents relatifs à l’application de ce traitement chez les athlètes. [less ▲]

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See detailH0LiCOW - III. Quantifying the effect of mass along the line of sight to the gravitational lens HE 0435-1223 through weighted galaxy counts★
Rusu, Cristian E.; Fassnacht, Christopher D.; Sluse, Dominique ULg et al

in Monthly Notices of the Royal Astronomical Society (2017), 467

Based on spectroscopy and multiband wide-field observations of the gravitationally lensed quasar HE 0435-1223, we determine the probability distribution function of the external convergence κ[SUB]ext[/SUB ... [more ▼]

Based on spectroscopy and multiband wide-field observations of the gravitationally lensed quasar HE 0435-1223, we determine the probability distribution function of the external convergence κ[SUB]ext[/SUB] for this system. We measure the under/overdensity of the line of sight towards the lens system and compare it to the average line of sight throughout the Universe, determined by using the CFHTLenS (The Canada France Hawaii Lensing Survey) as a control field. Aiming to constrain κ[SUB]ext[/SUB] as tightly as possible, we determine under/overdensities using various combinations of relevant informative weighting schemes for the galaxy counts, such as projected distance to the lens, redshift and stellar mass. We then convert the measured under/overdensities into a κ[SUB]ext[/SUB] distribution, using ray-tracing through the Millennium Simulation. We explore several limiting magnitudes and apertures, and account for systematic and statistical uncertainties relevant to the quality of the observational data, which we further test through simulations. Our most robust estimate of κ[SUB]ext[/SUB] has a median value κ^med_ext = 0.004 and a standard deviation σ[SUB]κ[/SUB] = 0.025. The measured σ[SUB]κ[/SUB] corresponds to 2.5 per cent relative uncertainty on the time delay distance, and hence the Hubble constant H[SUB]0[/SUB] inferred from this system. The median κ^med_ext value varies by ˜0.005 with the adopted aperture radius, limiting magnitude and weighting scheme, as long as the latter incorporates galaxy number counts, the projected distance to the main lens and a prior on the external shear obtained from mass modelling. This corresponds to just ˜0.5 per cent systematic impact on H[SUB]0[/SUB]. The availability of a well-constrained κ[SUB]ext[/SUB] makes HE 0435-1223 a valuable system for measuring cosmological parameters using strong gravitational lens time delays. [less ▲]

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See detailForeign Policy & International Development
Carlsen, Henrik; Pearson, Nakia ULg

in High-end Climate Change Policy Booklet (2017)

The conceptual framework for the chapter is based on the notion of “transnational climate impacts” (Benzie et al, 2016). By this we mean impacts that will require adaptation in the EU as a result of ... [more ▼]

The conceptual framework for the chapter is based on the notion of “transnational climate impacts” (Benzie et al, 2016). By this we mean impacts that will require adaptation in the EU as a result of climate change in other countries. [less ▲]

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See detailRegistered partnerships
Wautelet, Patrick ULg

in Basedow, Jürgen; Ferrari, Franco; de Miguel Asensio, Pedro (Eds.) et al EUROPEAN ENCYCLOPEDIA OF PRIVATE INTERNATIONAL LAW (2017)

This entry in the European Encyclopedia of Private International Law attempts to present the current state of the law in relation to registered partnerships. After an overview of the relevant sources ... [more ▼]

This entry in the European Encyclopedia of Private International Law attempts to present the current state of the law in relation to registered partnerships. After an overview of the relevant sources, attention is paid to the issue of characterization. The law applicable to the access to partnerships and effects of such partnerships is also covered. [less ▲]

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See detailNew data on the Mesozoic radiation of chelonioids
Scavezzoni, Isaure ULg; Fischer, Valentin ULg

Poster (2017, June)

"Turtles" (Testudines) form a successful group of reptiles with several terrestrial, marine and fresh-water species. Their peculiar and somewhat constrained morphology (i. e. : carapace incorporating ribs ... [more ▼]

"Turtles" (Testudines) form a successful group of reptiles with several terrestrial, marine and fresh-water species. Their peculiar and somewhat constrained morphology (i. e. : carapace incorporating ribs, curved limbs, anapsid skull exempt of temporal fenestrae) and ecology has often obscured their relationships and, hence, their evolutionary history, notably in marine turtles (chelonioids). Modern chelonioids are divided in two clades (i. e. : shoft-shelled turtles and hard-shelled turtles) supported by distinct morphological and embryological characters. Their origin is traced back up to the Cretaceous, along with a series of extinct forms, many of which being collectively known as Protostegidae. Fossil evidence show that at least five clades of marine turtles were roaming the seas at the end of the Cretaceous. In fact, chelonioids appeared during the first stages of the Early Cretaceous and quickly exploded to reach a high level of disparity at the lowermost part of the late Cretaceous. Therefore, the Mesozoic radiation of chelonioids must have happened during the "middle" Cretaceous (especially the Aptian-Albian interval). However this radiation is poorly understood as the phylogenetic relationships of marine turtles are not resolved yet. Bringing new data may help resolve these issues, and it is the exact reason why the genus Rhinochelys is being investigated. [less ▲]

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See detailHic Sunt NATs: Uncovering Address Translation with a Smart Traceroute
Zullo, Raffaele; Pescapé, Antonio; Edeline, Korian ULg et al

in IEEE/IFIP Workshop on Mobile Network Measurement (MNM) (2017, June)

Middleboxes are pervasive in today's Internet as they are deployed for an increasing number of reasons. An example is the network address translation (NAT), one of the first task to be performed to cope ... [more ▼]

Middleboxes are pervasive in today's Internet as they are deployed for an increasing number of reasons. An example is the network address translation (NAT), one of the first task to be performed to cope with the lack of IPv4 addresses. Recently the landscape for NATs has become even more crowded, especially in mobile networks, mainly due to the impossibility of IPv6 to be a large-scale solution to addressing issues. In this paper, we present a novel methodology for detecting NATs embodied in Mobile Tracebox, a measurement tool for Android smart devices that detects a wide range of middleboxes. It analyzes ICMP time-exceeded messages received during \traceroute and points at IP and transport checksum inconsistencies in the embedded packets to uncover address translation along a path. We deployed Mobile Tracebox through a crowdsourcing approach and used the collected dataset to validate our methodology. Results showed that, in absence of middleboxes breaking \traceroute, it can help to detect and locate NATs in the majority of the cases. [less ▲]

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See detailTowards a Renewed Alias Resolution with Space Search Reduction and IP Fingerprinting
Grailet, Jean-François ULg; Donnet, Benoît ULg

in Network Traffic Measurement and Analysis Conference (TMA) (2017, June)

Since the early 2000's, the Internet Topology has been frequently described and modeled from the perspective of routers. To this end, alias resolution mechanisms have been developed in order to aggregate ... [more ▼]

Since the early 2000's, the Internet Topology has been frequently described and modeled from the perspective of routers. To this end, alias resolution mechanisms have been developed in order to aggregate all IP interfaces of a router, collected with traceroute, into a single identifier. So far, many active measurement techniques have been considered, often taking advantage of specific features from network protocols. However, a lot of these methods have seen their efficiency decrease over time due to security reinforcements across the Internet. In this paper, we introduce a generic methodology to conduct efficient and scalable alias resolution. It combines the space search reduction of TreeNET (a tool for efficiently discovering subnets) with a fingerprinting process used to assess the feasibility of several state-of-the-art alias resolution methods, using a small, fixed amount of probes. We validate our method along MIDAR on an academic groundtruth and demonstrate that our methodology can achieve similar accuracy while using less probes and discovering subnets in the process. We further evaluate our method with measurements made on PlanetLab towards several distinct ASes of varying sizes and roles in the Internet. The collected data shows that some properties of our fingerprints correlate with each other, hinting some observed profiles could be linked with equipment vendors. Both TreeNET (which implements our methodology) and our dataset are freely available. [less ▲]

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See detailDecoding the disciplines – A pilot study at the University of Liège (Belgium)
Verpoorten, Dominique ULg; Devyver, Julie ULg; Duchâteau, Dominique ULg et al

in Andersson, Roy (Ed.) Proceedings of the 2nd EuroSoTL Conference (2017, June)

This paper reports on a first attempt to apply the two first stages of the “Decoding the disciplines” framework (Pace, 2017) at the University of Liège (Belgium). In this context, 7 professors volunteered ... [more ▼]

This paper reports on a first attempt to apply the two first stages of the “Decoding the disciplines” framework (Pace, 2017) at the University of Liège (Belgium). In this context, 7 professors volunteered to reflect, through a structured process, upon “bottlenecks” in their courses, with the help of IFRES’ (Institute for Training and Research in Higher Education) pedagogical advisers. This pilot delivered contrasted observations: while participants granted value to their exposure to this approach, especially in terms of enhanced awareness of possible discrepancies between what experts and newcomers in the field might consider as obvious, none of them activated the possibility offered to tackle the identified bottlenecks, according to the systematic approach (stages 3-7) suggested by the framework. The paper presents the pedagogical setting, analyses the interviews of participants and the outcomes of the project, outlines explanations for its results, and shares some lessons learnt. [less ▲]

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See detailUntargeted serum metabolite profiling of colorectal cancer using GC-Orbitrap technology
Di Giovanni, Nicolas ULg; Cojocariu, C; Silcock, P et al

Poster (2017, June)

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See detailDocumenting the parameters of effective SoTL counselling
Jérôme, Françoise ULg; Verpoorten, Dominique ULg; Detroz, Pascal ULg

in Andersson, Roy (Ed.) Proceedings of the 2nd EuroSoTL Conference (2017, June)

The Specialized Master in Higher Education Pedagogy (Formasup) organized at the University of Liège (Belgium) aims at the professional development of teachers involved in Higher Education. The training ... [more ▼]

The Specialized Master in Higher Education Pedagogy (Formasup) organized at the University of Liège (Belgium) aims at the professional development of teachers involved in Higher Education. The training programme gives participants the opportunity to make a full-scale SoTL study (from the implementation of a well-circumscribed course regulation to the assessment of its pedagogical effectiveness by means of the analysis of collected data) of one prominent aspect of their teaching practice. The process of trying out some new pedagogical approach and of discussing its effects on student learning has also to be reported in the form of a scientific paper (including a short review of the relevant pedagogical literature) and presented to a small audience of teacher colleagues. In order to meet the many requirements of such a complex task, each participant benefits from individualized pedagogical counselling. Besides a brief description of the Formasup context, the present contribution proposes brief case studies of three SoTL projects carried out in 2016. The case studies focus mainly on the dynamics of the interaction between teacher and pedagogical counsellor at each constitutive step of the SoTL project with the intention of making out the specificities of counselling applied to first time SoTL experience (time dedicated to and types of counselling activities in relation to the particularities of individual projects). The case studies are then integrated into a bigger picture drawing upon a larger number of counselling experiences over the last four years (from 2013 to 2016). On the basis of the main characteristics of 21 counselling experiences we propose a typology of teacher profiles according to their strategic approach to SoTL and the corresponding input of counselling. [less ▲]

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See detailMulti-instrument study of the hourly pulsations in Saturn's magnetophere
Palmaerts, Benjamin ULg

Doctoral thesis (2017)

The exploration of the magnetospheres of Jupiter and Saturn has revealed various periodic processes. Some periodicities are related to the planetary rotation while some others are characterized by a short ... [more ▼]

The exploration of the magnetospheres of Jupiter and Saturn has revealed various periodic processes. Some periodicities are related to the planetary rotation while some others are characterized by a short period. In Saturn's magnetosphere, periodicities of about one hour have been reported in the measurements of charged particle fluxes, plasma wave emissions, magnetic field strength and auroral emission brightness. The frequency, the spatial distribution and the magnetospheric process generating these hourly periodicities are still unknown. Similar short-period pulsations have been also observed in Jupiter's magnetosphere, suggesting that these 1-hour periodicities are the signature of a fundamental process in the magnetospheres of these two giant planets. In this thesis, I performed a thorough analysis of these hourly periodicities at Saturn using the data sets of several instruments on board the Cassini spacecraft in orbit around the giant planet since 2004. First I made a survey of the quasi-periodic 1-hour energetic electron pulsations observed in Saturn's magnetosphere between 2004 and 2014 by the Cassini particle instrumentation. These pulsations appear in the electron fluxes at energies between a hundred keV up to several MeV. The survey includes 720 pulsed electron events observed in the outer magnetosphere over a wide range of latitudes and local times, revealing that this phenomenon is common and frequent in Saturn's magnetosphere. A statistical analysis on the morphological properties of the pulsed events suggests a high-latitude source for the pulsed energetic electrons. I also investigated the simultaneous signatures of the electron pulsations in the radio emissions and the magnetic field measured by Cassini. The results of the multi-instrument study support the scenario of a high-latitude electron source and suggest a possible relation with the auroral processes. Images of Saturn's auroral emissions, which display the ionospheric response to magnetospheric dynamics, have been investigated to highlight any hourly pulsations. A high-latitude auroral spot exhibits quasi-periodic brightening with a periodicity of around 60 minutes. This auroral spot is associated with the magnetospheric cusp and high-latitude magnetopause reconnection in the lobes. Pulsed dayside magnetopause reconnection is likely a common triggering process for the cusp auroral brightening and for the high-latitude energetic electron pulsations. Finally, analysis of the plasma environment with low-energy electron measurements provided evidence of the presence of energetic electron pulsed events in the close vicinity of the magnetopause. Therefore it is suggested that processes at the magnetopause, most likely magnetic reconnection induced by instabilities, generate the hourly electron pulsations located at low latitude. The multi-instrument study achieved in my thesis sets constraints on the origin of the pulsed electron events and bring forward our current understanding on the hourly pulsations in Saturn's magnetosphere. [less ▲]

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See detailRégulation de voies de signalisation par deux acteurs de la voie Nonsense-mediated Decay, Dhx34 et Nbas: la cas particulier de l'adénohypophyse.
Windhausen, Thomas ULg

Doctoral thesis (2017)

In eukaryotes, biosynthesis of functional mRNAs is the core process of genetic expression and is monitored by highly conserved pathways that prevent appearance of aberrant mRNAs. Amongst them the Nonsense ... [more ▼]

In eukaryotes, biosynthesis of functional mRNAs is the core process of genetic expression and is monitored by highly conserved pathways that prevent appearance of aberrant mRNAs. Amongst them the Nonsense-Mediated Decay (NMD) pathway is the surveillance mechanism that detects and degrades mRNAs containing premature termination codons (PTCs). The translation of transcripts containing such nonsense codon within the coding sequence would leads to the production of C-terminally truncated proteins that could exhibit dominant negative or gain-of-function activities. The NMD is thus a key determinant of the phenotypic outcome of numerous diseases involving PTCs such as the β-thalassemia, the Duchenne muscular dystrophy or even some cancers. In addition to its quality control function degrading aberrant mRNA, the NMD is also involved in the abundance regulation of several physiological transcripts. For example the NMD is involved in the regulation of the concentration of splicing factors in a process called AS-NMD (Alternative splicing- Nonsense-mediated Decay), establish a threshold for some stress responses such as the UPR pathway (Unfolded Protein Response) and constitute a defence mechanism against ARN(+) viruses. Despite tremendous studies, the study of the developmental and physiological impact of the NMD pathway is restrained due to the early lethality of the mammals embryos that underwent knock-out of one of the NMD actor. As an alternative model we propose Danio rerio which as a vertebrate with external development and a large panel of genetic inactivation methods is a wonderful model for developmental studies and represent a excellent tool to study the NMD pathway. Initial studies in zebrafish conducted by morpholino knock-down, showed that depletion of upf1, upf2, smg5, smg6, dhx34 or nbas leads to the NMD blockage and induce similar developmental defects mainly in brain, eyes and somites. Moreover, it’s has been showed that as in mammals the NMD in fish also implicated in the regulation of natural transcripts. We present here a functional study of two key actors of the NMD, Dhx34 and Nbas, in the interesting case of the pituitary gland development. In the present study, we shed light on the NMD pathway importance for the developmental process of the pituitary gland. Using in situ hybridization confirmed by RT-qPCR quantification, we observed that the NMD inactivation thought inhibition of two crucial actors of this surveillance pathway, Dhx34 and Nbas, lead to a hypertrophy of the gland coupled with a promotion of the anterior cell fates and a repression of the posterior fates at 2 dpf. We proved that this endocrine deregulation is due to a late general increase of the Sonic Hedgehog and Delta-Notch signalling during AH formation. In addition to previous works, our results show that the NMD pathway is required to control the activity diverse signalling pathways involved in the developmental process. As confirmation, we could observe serious abnormalities in a variety of tissues such as underdeveloped eyes, intestine, liver and skeleton, defects in brain, somites and vascular patterning. [less ▲]

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See detailPhysiopathologie des tendinopathies
Kaux, Jean-François ULg

Conference (2017, May 28)

Le tendon, tissu conjonctif fibreux, mécaniquement responsable de la transmission de la force des muscles vers les os, constitue une entitédynamique qui, en fonction des contraintes, se restructure en ... [more ▼]

Le tendon, tissu conjonctif fibreux, mécaniquement responsable de la transmission de la force des muscles vers les os, constitue une entitédynamique qui, en fonction des contraintes, se restructure en permanence et, ce, grâce à diverses modifications métaboliques et mécaniques. Cetterevue décrit l’histologie, la vascularisation et l’innervation du tendon sain. De plus, la biomécanique et les réponses physiologiques tendineuses,ainsi que la physiopathologie de la tendinopathie y sont abordées. [less ▲]

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