Specialised master (Dissertations and theses)
Biochemical markers and radiographic scores as an evaluation for the osteochondral status of Warmblood stallions
Verwilghen, Denis
2009
 

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Abstract :
[en] Establishing the osteoarticular status of the horse is often performed by means of radiological screening of the animals. Widespread blood sampling could reveal to be an interesting alternative to this procedure which is time consuming and sometimes technically difficult. The aim of this study was to investigate the relationship between the radiological status of the horses and the levels of biochemical markers of cartilage degradation and synovial inflammation. A specific radiological scoring and classification system was therefore developed and applied on 63 stallions presented for studbook admission. Additionally, groups of horses were established according to the occurrence of osteochondrosis, degenerative joint disease and distal interphalangeal joint effusion. Insulin growth factor-I, myeloperoxidases, Coll2-1 and Coll2-1NO2 were used as blood markers. The combination of the blood parameters did not seem to correlate with the used scoring system. Coll2-1NO2 levels however tended to increase with poorer radiological class and this could therefore potentially be a useful predictor of the osteoarticular status in the horse. Coll2-1 levels were significantly higher in the degenerative joint disease group. A high percentage of horses with distal interphalangeal joint effusion was present in this study and was associated with decreased IGF-I and increased Coll2
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Verwilghen, Denis ;  Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Anesthésiologie gén. et pathologie chirurg. des grds animaux
Language :
English
Title :
Biochemical markers and radiographic scores as an evaluation for the osteochondral status of Warmblood stallions
Alternative titles :
[fr] Marquers biologiques et score radiologique comme outil d'evaluation du status osteoarticulaire chez des etalons de sport Belge
Defense date :
2009
Institution :
ULiège - Université de Liège
Degree :
DES: Diplome d'Etude Specialisé en chirurgie des grands animaux
Promotor :
Serteyn, Didier  ;  Université de Liège - ULiège > Département d'Enseignement et de Clinique des Equidés (DCE) > Chirurgie des équidés
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since 19 March 2010

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