Unpublished conference/Abstract (Scientific congresses and symposiums)
Integrated continuous flow photoreactors: Photooxidation of (L)-methionine with singlet oxygen
Emmanuel, Noémie; Monbaliu, Jean-Christophe
2017Journée du département de chimie de l'ULiège
 

Files


Full Text
Noemie_Emmanuel_abstract _JDD.docx
Publisher postprint (71.15 kB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
(L)-methionine; microfluidics; photooxidation; singlet oxygen; continuous-flow
Abstract :
[en] Development of photochemistry in macroscopic batch reaction vessels is hampered due to inherent limitations: light penetration remains superficial, resulting in inhomogeneous irradiation and hence to side-reactions or product degradation due to overexposure. The recent implementation of photochemical processes in microreactors under continuous-flow conditions appeared to be much more powerful than its batch analogue in terms of irradiation efficiency and light penetration. Furthermore, the fine control of residence time ensures an accurate control of the irradiation time, avoiding side-reactions and degradation. The scalable photooxidation of (L)-methionine with singlet oxygen using Rose Bengal as a sensitizer was successfully implemented in a microreactor setup and led to total and selective conversion into methionine sulfoxide, an important building block for the organic synthesis of peptides or functionalized amino acid. The reaction was performed in less than 1 min while the same reaction in batch took 2 h. Other substrates as α-terpinene or citronellol were also photooxidized into high added value compounds using the same conditions.
Disciplines :
Chemistry
Author, co-author :
Emmanuel, Noémie ;  Université de Liège - ULiège > Département de chimie (sciences) > Center for integrated Technology and Organic Synthesis
Monbaliu, Jean-Christophe  ;  Université de Liège - ULiège > Département de chimie (sciences) > Center for integrated Technology and Organic Synthesis
Language :
English
Title :
Integrated continuous flow photoreactors: Photooxidation of (L)-methionine with singlet oxygen
Publication date :
06 July 2017
Event name :
Journée du département de chimie de l'ULiège
Event date :
06 juillet 2017
Available on ORBi :
since 22 October 2017

Statistics


Number of views
35 (2 by ULiège)
Number of downloads
7 (1 by ULiège)

Bibliography


Similar publications



Contact ORBi