p16ink4 and cytokeratin 7 immunostaining in predicting HSIL outcome for low-grade squamous intraepithelial lesions: A case series, literature review and commentary
Herfs, Michael ✱; Université de Liège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques
Crum, Christopher ✱
✱ These authors have contributed equally to this work.
Language :
English
Title :
p16ink4 and cytokeratin 7 immunostaining in predicting HSIL outcome for low-grade squamous intraepithelial lesions: A case series, literature review and commentary
Publication date :
2016
Journal title :
Modern Pathology
ISSN :
0893-3952
eISSN :
1530-0285
Publisher :
Lippincott Williams & Wilkins, Hagerstown, United States - Maryland
Sano T, Oyama T, Kashiwabara K et al. Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions. Am J Pathol 1998;153:1741-1748.
Darragh TM, Colgan TJ, Cox JT et al. The lower anogenital squamous terminology standardization project for HPV-associated lesions: Background and consensus recommendations from the college of American pathologists and the american society for colposcopy and cervical pathology. Arch Pathol Lab Med 2012;136:1266-1297.
Herfs M, Yamamoto Y, Laury A et al. A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer. Proc Natl Acad Sci USA 2012;109:10516-10521.
Sagasta A, Castillo P, Saco A et al. p16 staining has limited value in predicting the outcome of histological low-grade squamous intraepithelial lesions of the cervix. Mod Pathol 2016;29:51-59.
The Atypical Squamous Cells of Undetermined Significance/ Low-Grade Squamous Intraepithelial Lesions Triage Study (ALTS) Group. Human papillomavirus testing for triage of women with cytologic evidence of low-grade squamous intraepithelial lesions: baseline data from a randomized trial. J Natl Cancer Inst 2000;92:397-402.
Nishio S, Fujii T, Nishio H et al. p16(INK4a) immunohistochemistry is a promising biomarker to predict the outcome of low grade cervical intraepithelial neoplasia: comparison study with HPV genotyping. J Gynecol Oncol 2013;24:215-221.
Hariri J, Øster A. The negative predictive value of p16INK4a to assess the outcome of cervical intraepithelial neoplasia 1 in the uterine cervix. Int J Gynecol Pathol 2007;26:223-228.
Wang X, Ouyang H, Yamamoto Y et al. Residual embryonic cells as precursors of a Barrett's-like metaplasia. Cell 2011;145:1023-1035.
Yang EJ, Quick MC, Hanamornroongruang S et al. Microanatomy of the cervical and anorectal squamocolumnar junctions: a proposed model for anatomical differences in HPV-related cancer risk. Mod Pathol 2015;28:994-1000.
Herfs M, Parra-Herran C, Howitt BE et al. Cervical squamocolumnar junction-specific markers define distinct, clinically relevant subsets of low-grade squamous intraepithelial lesions. Am J Surg Pathol 2013;37: 1311-1318.
Paquette C, Mills AM, Stoler MH. Predictive value of cytokeratin 7 immunohistochemistry in cervical lowgrade squamous intraepithelial lesion as a marker for risk of progression to a high-grade lesion. Am J Surg Pathol 2016;40:236-243.
Cox JT, Schiffman M, Solomon D. Prospective followup suggests similar risk of subsequent cervical intraepithelial neoplasia grade 2 or 3 among women with cervical intraepithelial neoplasia grade 1 or negative colposcopy and directed biopsy. Am J Obstet Gynecol 2003;188:1406-1412.
Moscicki AB, Ma Y, Wibbelsman C et al. Rate of and risks for regression of cervical intraepithelial neoplasia 2 in adolescents and young women. Obstet Gynecol 116:1373-1380.
Moscicki AB, Shiboski S, Hills NK et al. Regression of low-grade squamous intra-epithelial lesions in young women. Lancet 2004;364:1678-1683.
Ostor AG. Natural history of cervical intraepithelial neoplasia: a critical review. Int J Gynecol Pathol 1993; 12:186-192.
Stoler MH, Schiffman M. Interobserver reproducibility of cervical cytologic and histologic interpretations: realistic estimates from the ASCUS-LSIL triage study. JAMA 2001;285:1500-1505.
Cai B, Ronnett BM, Stoler M et al. Longitudinal evaluation of interobserver and intraobserver agreement of cervical intraepithelial neoplasia diagnosis among an experienced panel of gynecologic pathologists. Am J Surg Pathol 2007;31:1854-1860.
Castle PE, Stoler MH, Solomon D et al. The relationship of community biopsy-diagnosed cervical intraepithelial neoplasia grade 2 to the quality control pathologyreviewed diagnoses: an ALTS report. Am J Clin Pathol 2007;127:805-815.
Carreon JD, Sherman ME, Guillén D et al. CIN2 is a much less reproducible and less valid diagnosis than CIN3: results from a histological review of populationbased cervical samples. Int J Gynecol Pathol 2007;26: 441-446.
Reuschenbach M, Wentzensen N, Dijkstra MG et al. p16INK4a immuno-histochemistry in cervical biopsy specimens: a systematic review and meta-analysis of the interobserver agreement. Am J Clin Pathol 2014;142:767-772.
Agoff SN, Lin P, Morihara J et al. p16(INK4a) expression correlates with degree of cervical neoplasia: a comparison with Ki-67 expression and detection of high-risk HPV types. Mod Pathol 2003;16:665-673.
Tringler B, Gup CJ, Singh M et al. Evaluation of p16INK4a and pRb expression in cervical squamous and glandular neoplasia. Hum Pathol 2004;35:689-696.
Keating JT, Cviko A, Riethdorf S et al. Ki-67, cyclin E, and p16INK4 are complimentary surrogate biomarkers for human papilloma virus-related cervical neoplasia. Am J Surg Pathol 2001;25:884-891.
Klaes R, Benner A, Friedrich T et al. p16INK4a immunohistochemistry improves interobserver agreement in the diagnosis of cervical intraepithelial neoplasia. Am J Surg Pathol 2002;26:1389-1399.
Kong CS, Balzer BL, Troxell ML et al. p16INK4A immunohistochemistry is superior to HPV in situ hybridization for the detection of high-risk HPV in atypical squamous metaplasia. Am J Surg Pathol 2007;31:33-43.
Maniar KP, Sanchez B, Paintal A et al. Role of the biomarker p16 in downgrading-CIN 2 diagnoses and predicting higher-grade lesions. Am J Surg Pathol 2015;39:1708-1718.
Cortecchia S, Galanti G, Sgadari C et al. Follow-up study of patients with cervical intraepithelial neoplasia grade 1 overexpressing p16Ink4a. Int J Gynecol Cancer 2013;23:1663-1669.
Pacchiarotti A, Ferrari F, Bellardini P et al. Prognostic value of p16-INK4A protein in women with negative or CIN1 histology result: a follow-up study. Int J Cancer 2014;134:897-904.
del Pino M, Garcia S, Fusté V et al. Value of p16(INK4a) as a marker of progression/regression in cervical intraepithelial neoplasia grade 1. Am J Obstet Gynecol 2009;201:488 e1-7.
Ozaki S, Zen Y, Inoue M. Biomarker expression in cervical intraepithelial neoplasia: potential progression predictive factors for low-grade lesions. Hum Pathol 2011;42:1007-1012.
Razmpoosh M, Sansregret A, Oligny LL et al. Assessment of correlation between p16INK4a staining, specific subtype of human papillomavirus, and progression of LSIL/CIN1 lesions: first comparative study. Am J Clin Pathol 2014;142:104-110.
Quint KD, de Koning MN, Quint WG et al. Progression of cervical low grade squamous intraepithelial lesions: in search of prognostic biomarkers. Eur J Obstet Gynecol Reprod Biol 2013;170:501-506.
Liao GD, Sellors JW, Sun HK et al. p16INK4A immunohistochemical staining and predictive value for progression of cervical intraepithelial neoplasia grade 1: a prospective study in China. Int J Cancer 2014;134: 1715-1724.
Mills AM, Paquette C, Castle PE et al. Risk stratification by p16 immunostaining of CIN1 biopsies: a retrospective study of patients from the quadrivalent HPV vaccine trials. Am J Surg Pathol 2015;39:611-617.
Smelov V, Elfstrom KM, Johansson AL et al. Long-term HPV type-specific risks of high-grade cervical intraepithelial lesions: a 14-year follow-up of a randomized primary HPV screening trial. Int J Cancer 2015;136: 1171-1180.
Massad LS, Einstein MH, Huh WK et al. 2012 updated consensus guidelines for the management of abnormal cervical cancer screening tests and cancer precursors. Obstet Gynecol 2013;121:829-846.
Prendiville W, Cullimore J, Norman S. Large loop excision of the transformation zone (LLETZ). A new method of management for women with cervical intraepithelial neoplasia. Br J Obstet Gynaecol 1989;96: 1054-1060.
Samson SL, Bentley JR, Fahey TJ et al. The effect of loop electrosurgical excision procedure on future pregnancy outcome. Obstet Gynecol 2005;105:325-332.
Maniar KP, Nayar R. HPV-related squamous neoplasia of the lower anogenital tract: an update and review of recent guidelines. Adv Anat Pathol 2014;21: 341-358. Erratum in: Adv Anat Pathol.
Chen EY, Tran A, Raho CJ et al. Histological 'progression' from low (LSIL) to high (HSIL) squamous intraepithelial lesion is an uncommon event and an indication for quality assurance review. Mod Pathol 2010;23:1045-1051.
