[en] Tributyltin (TBT) and triphenyltin (TPT) are emblematic endocrine disruptors, which have been mostly studied in gonochoric prosobranchs. Although both compounds can simultaneously occur in the environment, they have mainly been tested separately for their effects on snail reproduction. Because large discrepancies in experimental conditions occurred in these tests, the present study aimed at comparing the relative toxicity of TBT and TPT under similar laboratory conditions in the 0–600 ng Sn/L range. Tests were performed on the simultaneous hermaphrodite Lymnaea stagnalis, a freshwater snail in which effects of TPT were unknown. Survival, shell length and reproduction were monitored in a 21d semi-static test. Frequency of abnormal eggs was assessed as an additional endpoint. TPT hampered survival while TBT did not. Major effects on shell solidity and reproduction were observed for both compounds, reproductive outputs being more severely hampered by TBT than by TPT. Considering the frequency of abnormal eggs allowed increasing test sensitivity, since snail responses to TBT could be detected at concentrations as low as 19 ng Sn/L. However, the putative mode of action of the two compounds could not be deduced from the structure of the molecules or from the response of apical endpoints. Sensitivity of L. stagnalis to TBT and TPT was compared to the sensitivity of prosobranch molluscs with different habitats and different reproductive strategies.
Disciplines :
Environmental sciences & ecology
Author, co-author :
Giusti, Arnaud ; Université de Liège - ULiège > Département de Biologie, Ecologie et Evolution > Ecologie animale et écotoxicologie
Barsi, Alpar; Institut Scientifique de Recherche Agronomique - INRA > UMR0985 Ecologie et Santé des Ecosystèmes > Equipe Ecotoxicologie et Qualité des milieux Aquatiques
Dugué, Maël; Institut Scientifique de Recherche Agronomique - INRA > UMR0985 Ecologie et Santé des Ecosystèmes > Equipe Ecotoxicologie et Qualité des Milieux Aquatiques
Collinet, Marc; Institut Scientifique de Recherche Agronomique - INRA > UMR0985 Ecologie et Santé des Ecosystèmes > Equipe Ecotoxicologie et Qualité des Milieux Aquatiques
Thomé, Jean-Pierre ; Université de Liège - ULiège > Département de Biologie, Ecologie et Evolution > Ecologie animale et écotoxicologie
Joaquim-Justo, Célia ; Université de Liège - ULiège > Département de Biologie, Ecologie et Evolution > Ecologie animale et écotoxicologie
Roig, Benoit; Ecole des Hautes Etudes en Santé Publique > LERES
Lagadic, Laurent; Institut Scientifique de Recherche Agronomique - INRA > UMR0985 Ecologie et Santé des Ecosystèmes > Equipe Ecotoxicologie et Qualité des Milieux Aquatiques
Ducrot, Virginie; Institut Scientifique de Recherche Agronomique - INRA > UMR0985 Ecologie et Santé des Ecosystèmes > Equipe Ecotoxicologie et Qualité des Milieux Aquatiques
Language :
English
Title :
Reproductive impacts of tributyltin (TBT) and triphenyltin (TPT) in the hermaphroditic freshwater gastropod Lymnaea stagnalis
Publication date :
July 2013
Journal title :
Environmental Toxicology and Chemistry
ISSN :
0730-7268
eISSN :
1552-8618
Publisher :
SETAC Press, Pensacola, United States - Florida
Volume :
32
Issue :
7
Pages :
1552-1560
Peer reviewed :
Peer Reviewed verified by ORBi
European Projects :
FP7 - 238148 - CREAM - Mechanistic Effect Models for the Ecological Risk Assessment of Chemicals
Funders :
FRIA - Fonds pour la Formation à la Recherche dans l'Industrie et dans l'Agriculture [BE] European Union (under the 7th Framework Programme project acronym CREAM, contract number PITN-GA-2009-238148) Programme Environnement-Santé-Travail de l’ANSES avec le soutient de l’ITMO cancer dans le cadre du plan cancer 2009-2013 CE - Commission Européenne [BE]
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