Abstract :
[en] A new quaternary indole alkaloid: 10-hydroxy-Nb-methyl-corynantheol has been isolated from the stem bark of Strychnos usambarensis by High Speed Counter Current Chromatography (HSCCC). Its IUPAC name is 2-(2-hydroxyethyl)-3-vinyl-5-methyl-1,2,3,4,6,7,12,12b-octahydro-indolo quinolizinium-9-ol. The structure was established by spectral (UV,IR,EIMS and NMR data) and chemical methods.The stereochemistry was proposedo n the basis of CD curve, NMR studies and biogenetic hypothesis.
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