Article (Scientific journals)
10-Hydroxy-Nb-methyl-corynantheol, a new quaternary alkaloid from the stem bark of Strychnos usambarensis
Quetin-Leclercq, Joëlle; Angenot, Luc
1988In Phytochemistry, 27 (6), p. 1923-1926
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Keywords :
Strychnos usambarensis; quaternary indole alkaloid; 10-hydroxy-Nb-methyl-corynantheol; HSCCC; counter-current chromatography
Abstract :
[en] A new quaternary indole alkaloid: 10-hydroxy-Nb-methyl-corynantheol has been isolated from the stem bark of Strychnos usambarensis by High Speed Counter Current Chromatography (HSCCC). Its IUPAC name is 2-(2-hydroxyethyl)-3-vinyl-5-methyl-1,2,3,4,6,7,12,12b-octahydro-indolo quinolizinium-9-ol. The structure was established by spectral (UV,IR,EIMS and NMR data) and chemical methods.The stereochemistry was proposedo n the basis of CD curve, NMR studies and biogenetic hypothesis.
Disciplines :
Chemistry
Pharmacy, pharmacology & toxicology
Author, co-author :
Quetin-Leclercq, Joëlle
Angenot, Luc  ;  Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Language :
English
Title :
10-Hydroxy-Nb-methyl-corynantheol, a new quaternary alkaloid from the stem bark of Strychnos usambarensis
Publication date :
1988
Journal title :
Phytochemistry
ISSN :
0031-9422
eISSN :
1873-3700
Publisher :
Pergamon Press, New York, United States - New York
Volume :
27
Issue :
6
Pages :
1923-1926
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 08 May 2010

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